Neisseria Gonorrhoea (NG) Nucleic Acid Detection Kit (PCR-Fluorescent Probe Method) CapitalBio

Features

High sensitivity: The LOD is 400 copies/ml;

Quick workflow: It only takes 1.5 h for the whole workflow;

Flexible sample types: Urine and genital tract secretion swabs are both applicable;

Simple use: Compatible with DxLab-32A Automated Nucleic Acid Purification and Real Time PCR System, enabling a sample in-report out workflow.

Test Method

The kit is designed based on PCR - fluorescent probe technology

Sample Types 

Urine and genital tract secretion swabs

Clinical Significance

Pre-pregnancy and in-pregnancy pathogen screening

Diseases tests, including inflammation of urogenital system, STDs, infertility, etc.

Order Information

Background Information

Neisseria gonorrhoeae (Ng) infections belong to the most frequent sexually transmitted infections worldwide with around 87 million new infections per year according to WHO estimations. Transmission of the bacteria is by direct mucosal contact and may lead to infections at the urethra, endocervix, rectum, pharynx, or conjunctiva. While 90% of male urethral infections present with discharge or dysuria, less than 50% of female urethral and cervical infections are symptomatic, and most rectal infections and almost all pharyngeal infections are asymptomatic. By transluminal dissemination, starting from the urethral or endocervical mucosa, Ng may cause ascending infections resulting in epididymo-orchitis, salpingitis, and pelvic inflammatory disease (PID). In rare cases, the bacteria may spread systemically resulting in severe complications like fever/septicemia, arthritis, tenosynovitis, endocarditis, or vasculitis. In addition, gonococcal infection in pregnancy is associated with adverse pregnancy outcomes, like low birth weight infants, small for gestational age infants, and transmission to newborns that may result in conjunctivitis (ophthalmia neonatorum) and oropharyngeal infections.